Description
What arrives in the package
The listing covers a single-component crystalline solid packed as a weighed laboratory unit.
- Substance name: tadalafil, supplied as a dry powder for analytical work
- CAS registry number 171596-29-5, matched against supplier catalogue records
- Molecular formula C22H19N3O4 with a formula weight of 389.4
- Declared assay of the main component: not less than 99 percent
- Net mass of the unit: 1000 mg, sealed in a labelled inner container
Confirming identity before anything else
Identity and purity are two separate questions, and identity is settled first.
- Read the registry number from the inner label against the certificate header
- Record an infrared spectrum and overlay it on a retained reference trace
- Match chromatographic retention with a standard injected in the same sequence
- Confirm the nominal mass expected from the summary formula by mass spectrometry
Routine assay technique
Reversed-phase liquid chromatography with ultraviolet detection is the workhorse for this molecular class.
- Dissolve in an organic solvent first, then dilute into the mobile phase
- Run a gradient when late-eluting related substances have to be resolved
- Take area normalisation as a first approximation and an external standard for the reported figure
- Inject system suitability solutions before the sample sequence, never afterwards
Classes of related substances
Levels belong on the batch certificate, so only the classes are described here.
- Unreacted starting material and isolated synthesis intermediates
- Stereochemical and positional by-products formed during ring closure
- Residual crystallisation solvents, quantified by headspace gas chromatography
- Water content by Karl Fischer titration, reported batch by batch
- Inorganic residue reported as sulfated ash
Bench handling and storage
Keep the powder dry and work inside a ventilated enclosure.
- Store the sealed container cool, dry and shielded from daylight
- Let the container reach room temperature before opening so moisture does not condense inside
- Weigh on a calibrated analytical balance behind a draught shield
- Log every withdrawal in the substance ledger with date, mass and operator
- Collect residues and rinsings as organic chemical waste
Paperwork that stays with the sample
A laboratory unit without its file is an unidentified solid.
- Batch number together with the manufacturing date
- Certificate of analysis naming the techniques actually applied
- Safety data sheet in the language of the receiving laboratory
- A retest date rather than an open-ended shelf life statement
Other catalogue items
- CBD / Cannabidiol / Cannabidiol, Krishals ≥ 99.85% 1000mg!
- Sunifiram, pure chemical ≥ 99%. 1000mg.
- L-DOPA ≥ 99%. Czysta substancja chemiczna bez wypełniaczy!
- Aniracetam ≥ 99%. Czysta substancja chemiczna bez wypełniaczy 1000mg.
Selected literature
Animal and in vitro studies indexed in PubMed; no human-use guidance is provided here.
- Greco EA Tadalafil and Steroid Hormones Interactions in Adipose, Bone and Prostate Tissues: Focus on Translational Perspectives 2022, International journal of molecular sciences. PMID 35457011
- Gong B Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis 2017, International urology and nephrology. PMID 28741090
- Jehle DVK Benefits of Tadalafil and Sildenafil on Mortality, Cardiovascular Disease, and Dementia 2025, The American journal of medicine. PMID 39532245
- Sebastianelli A Tadalafil Alone or in Combination with Tamsulosin for the Management for LUTS/BPH and ED 2020, Current urology reports. PMID 33108544
Material status. It is not a substance for human use. No veterinary applications are provided for. This is a high-purity laboratory reagent intended for analytical work by HPLC and GC-MS. Outside the category of medicinal and food products.
