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Description

Which numbers identify this substance beyond the trade name?

The registry number is 314728-85-3, the molecular formula is C14H18N2O2 and the molecular weight is 246.30. The catalogue synonym DM-235 appears on most supplier pages and is worth recording alongside the registry number, since ordering systems index the two differently. Structurally the molecule is a piperazine ring carrying a benzoyl group on one nitrogen and a propanoyl group on the other. See also our catalogue listing: ALCAR / Acetylo-L-Karnityna – Czystość ≥ 99% masa .

What separates a laboratory lot from technical-grade material?

Technical material is sold on appearance and yield, while a laboratory lot is sold on a documented assay obtained by a named method. Reference-standard suppliers typically certify this compound at 98 percent or better and state the technique used to reach that figure. The difference is not the powder in the vial but the paperwork that makes the powder usable as a comparison point.

How is identity confirmed on receipt?

Identity rests on two independent legs: a spectroscopic confirmation of structure and a chromatographic comparison against a certified standard. Proton and carbon nuclear magnetic resonance distinguish the two acyl groups clearly, and mass spectrometry supports the molecular weight. Neither leg alone is sufficient, because a matching mass can belong to more than one arrangement of the same atoms.

Which impurities are plausible for this scaffold?

Two amide bonds and a symmetrical starting ring make the plausible list short and predictable: mono-acylated piperazine intermediates, unreacted piperazine, and the carboxylic acids released if either amide hydrolyses. Process solvents and water complete the list. Each of these needs its own determination, since none of them is guaranteed to appear in an ultraviolet chromatogram optimised for the main component.

What does a purity figure leave unmeasured?

A chromatographic purity figure describes the ratio of peak areas under one set of conditions and nothing else. Water content, inorganic residue and solvent traces sit outside it entirely and are reported separately when the certificate is complete. A vial can be 99 percent pure by chromatography and still carry several percent of water by mass. See also our reagent-grade material: Fenyloalanina / L-Phenylalanine ≥ 99% 1000mg.

How should the vial be stored and opened?

Amides hydrolyse in the presence of moisture, so the container stays closed, dry and cool, and a cold vial is allowed to reach room temperature before the cap is turned. Weighing is done quickly, with the vial reclosed between operations. A desiccator is the right home for an opened unit that will be used across several sessions.

  • Registry number 314728-85-3, formula C14H18N2O2, mass 246.30, synonym DM-235.
  • Assay figure is method-bound; ask which technique produced it.
  • Water, residual solvents and inorganic residue are separate determinations.
  • Plausible impurities follow the acylation route: mono-acylated ring, free piperazine, released acids.
  • Store dry and cool, equilibrate before opening, archive the certificate with the chromatogram.

See also

Selected literature

Animal and in vitro studies indexed in PubMed; no human-use guidance is provided here.

  • Agha KA Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening 2022, Journal of enzyme inhibition and medicinal c. PMID 35484855
  • Martini E Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers 2009, Bioorganic & medicinal chemistry. PMID 19786353
  • Moriguchi S Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-aspartate receptor 2013, Hippocampus. PMID 23733502
  • Galeotti N AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram) 2003, Naunyn-Schmiedeberg's archives of pharmacolo. PMID 14600801

Material status. Human use is outside the scope of this product. It is not a veterinary product either. A high-purity laboratory product used in HPLC and GC-MS studies. It is neither a medicinal product nor a foodstuff.

Additional information
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