{"id":546,"date":"2022-10-04T16:59:11","date_gmt":"2022-10-04T16:59:11","guid":{"rendered":"https:\/\/mebicar.pl\/sklep\/forskolin-forksolin-purity-%e2%89%a599-1000mg\/"},"modified":"2026-08-13T18:24:26","modified_gmt":"2022-10-22T17:36:51","slug":"forskolin-forksolin-purity-%e2%89%a599-1000mg","status":"publish","type":"product","link":"https:\/\/mebicar.pl\/en\/sklep\/forskolin-forksolin-purity-%e2%89%a599-1000mg\/","title":{"rendered":"Forskolin 1 g reagent: identity, assay and release records"},"content":{"rendered":"\n\n
Zestawienie parametr\u00f3w materia\u0142u<\/caption>
Parameter<\/th>Value<\/th><\/tr><\/thead>
CAS number<\/td>66575-29-9<\/td><\/tr>\n
Empirical formula<\/td>C22H34O7<\/td><\/tr>\n
Molar mass<\/td>410.5 g\/mol<\/td><\/tr>\n
Compound class<\/td>labdane-type diterpenoid<\/td><\/tr>\n
Botanical origin<\/td>root of Coleus forskohlii, catalogued also as Plectranthus barbatus<\/td><\/tr>\n
Net mass in the unit<\/td>1000 mg<\/td><\/tr>\n
Purity declared on the label<\/td>≥ 99%<\/td><\/tr>\n
Physical form<\/td>solid, powdered<\/td><\/tr>\n
Primary packaging<\/td>sealed aluminium pouch<\/td><\/tr>\n
Storage temperature and retest date<\/td>as stated on the certificate of analysis<\/td><\/tr>\n<\/tbody><\/table>\n\n\n\n

Confirming the labdane skeleton<\/h2>\n\n\n\n

The molecule is a highly oxygenated bicyclic diterpene: several hydroxyl groups, one acetate ester and a vinyl substituent on a rigid decalin-derived framework. Identity is confirmed against a certified reference standard rather than assumed from a label. Three independent lines normally close the question \u2014 retention agreement in a reversed-phase system, an infrared spectrum superimposable with the standard, and resonance patterns consistent with the polyoxygenated framework. Where no standard is on hand, the container stays marked as identity-pending in the register.<\/p>\n\n\n\n

Assay and chromatographic separation<\/h2>\n\n\n\n

This diterpene carries no strong chromophore, so ultraviolet detection works only at short wavelengths, where the mobile phase itself starts to absorb. Control laboratories therefore run charged aerosol or evaporative light scattering detection alongside low-wavelength ultraviolet, using an acetonitrile-water gradient on an octadecyl phase. Area normalisation returns a chromatographic purity figure, which is not the same quantity as an assay against a standard, and the certificate has to say which of the two it quotes. See also our reagent-grade material: ALCAR \/ Acetylo-L-Karnityna – Czysto\u015b\u0107 \u2265 99% masa <\/a>.<\/p>\n\n\n\n

Impurities carried over from the plant matrix<\/h2>\n\n\n\n

Material of botanical origin brings a family of structurally close congeners with it \u2014 isoforskolin, the deoxy analogues and related labdanes formed alongside the main compound in the root. They elute near the principal peak and are the usual reason a batch misses a tight specification. Beyond them, a complete batch file covers residual solvents from extraction and crystallisation, water content by Karl Fischer titration, sulphated ash and elemental impurities. Chromatographic purity on its own therefore never closes the assessment.<\/p>\n\n\n\n