{"id":545,"date":"2022-10-10T08:24:56","date_gmt":"2022-10-10T08:24:56","guid":{"rendered":"https:\/\/mebicar.pl\/sklep\/l-tyrosine-l-tyrosine-tyrosine-purity-%e2%89%a5-99-1000mg\/"},"modified":"2026-08-13T18:24:26","modified_gmt":"2022-10-10T08:24:56","slug":"l-tyrosine-2","status":"publish","type":"product","link":"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/","title":{"rendered":"L-Tyrosine Crystalline Powder: Specification Sheet and Purity Assessment Routes"},"content":{"rendered":"\n<table><caption>Zestawienie parametr\u00f3w materia\u0142u<\/caption>\n<th scope=\"row\"ead><tr><th scope=\"row\">Parameter<\/th><th scope=\"row\">Value<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Substance<\/td><td>L-tyrosine, proteinogenic amino acid, synthetic material<\/td><\/tr>\n<tr><td>CAS registry number<\/td><td>60-18-4<\/td><\/tr>\n<tr><td>Summary formula<\/td><td>C9H11NO3<\/td><\/tr>\n<tr><td>Formula weight<\/td><td>181.19<\/td><\/tr>\n<tr><td>Configuration<\/td><td>L, single stereocentre in the side chain<\/td><\/tr>\n<tr><td>Appearance<\/td><td>White crystalline powder<\/td><\/tr>\n<tr><td>Declared assay<\/td><td>Not less than 99 percent of the main component<\/td><\/tr>\n<tr><td>Net mass<\/td><td>1000 mg per sealed unit<\/td><\/tr>\n<tr><td>Solubility character<\/td><td>Sparingly soluble in water, dissolves in dilute acid and in alkali<\/td><\/tr>\n<tr><td>Water content<\/td><td>By Karl Fischer titration or loss on drying, per batch<\/td><\/tr>\n<tr><td>Sulfated ash<\/td><td>Determined per batch and stated on the certificate<\/td><\/tr>\n<tr><td>Storage<\/td><td>Cool, dry, sealed, protected from light<\/td><\/tr>\n<\/tbody>\n<\/table>\n\n\n\n<h2 class=\"wp-block-heading\">What the phenol group changes for the analyst<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Among the standard amino acids this one carries a phenolic hydroxyl on an aromatic ring, and that single structural detail governs most of the analytical work. The ring gives a genuine ultraviolet chromophore, so direct detection is possible where aliphatic amino acids demand derivatisation. The same hydroxyl makes the molecule susceptible to oxidation, which is why discoloured material is held rather than used.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Assay routes and their limits<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Classical ion-exchange separation with post-column ninhydrin detection remains the reference approach for amino acid material and copes well with a crystalline solid of this kind. Reversed-phase liquid chromatography with ultraviolet detection is faster and takes advantage of the aromatic ring directly. Non-aqueous acid-base titration gives a total figure for the amino acid function but says nothing about which amino acid is present, so it never closes identity on its own. See also our catalogue listing: <a href=\"\/sklep\/acetyl-l-carnitine\/\">ALCAR \/ Acetyl-L-Carnitine &#8211; Purity \u2265 99% net weig<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Chemical purity against optical purity<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">These two properties are measured separately and confusing them is the commonest error on a receiving bench. Chemical assay answers how much of the sample is tyrosine in any configuration; optical purity answers how much of that tyrosine is the L form. The second requires either a chiral stationary phase or a polarimetric determination under defined conditions, and the result belongs on the batch certificate.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Confirm the registry number on the inner label against the certificate header<\/li>\n<li>Record an infrared spectrum and compare it with a retained reference trace<\/li>\n<li>Run the assay by a method the certificate actually names<\/li>\n<li>Request optical purity explicitly when the application depends on configuration<\/li>\n<li>Log water content and sulfated ash as parameters separate from the assay<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Handling, dissolution and storage<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Because the solid is poorly soluble in neutral water, stock solutions are usually made in dilute hydrochloric acid or dilute alkali and then adjusted, and the preparation route is recorded with the solution. Warming to force dissolution risks degradation of the phenolic ring and is a poor substitute for pH adjustment. The sealed container is kept cool, dry and dark, brought to room temperature before opening, and every withdrawal is entered in the substance ledger. See also our laboratory reagent: <a href=\"\/sklep\/mebicar-2\/\">Mebicar \/ Mebicar \/ Temgicoluril &#8211; 30x capsules 10<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Related reagents<\/h2>\n\n\n\n<ul class=\"powiazane-odczynniki wp-block-list\">\n<li><a href=\"\/sklep\/mebicar-2\/\">Mebicar \/ Mebicar \/ Temgicoluril &#8211; 30x capsules 100mg. Purity \u2265 99%<\/a><\/li>\n<li><a href=\"\/sklep\/acetyl-l-carnitine\/\">ALCAR \/ Acetyl-L-Carnitine &#8211; Purity \u2265 99% net weight 1000mg.<\/a><\/li>\n<li><a href=\"\/sklep\/l-phenylalanine\/\">Fenyloalanina \/ L-Phenylalanine \u2265 99% 1000mg<\/a><\/li>\n<li><a href=\"\/sklep\/methylene-blue\/\">Methylene Blue \/ B\u0141\u0118KIT METYLENOWY. Czysto\u015b\u0107 \u2265 99.50% 1000mg.<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">References<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Animal and in vitro studies indexed in PubMed; no human-use guidance is provided here.<\/p>\n\n\n\n<ul class=\"pismiennictwo wp-block-list\">\n<li>Mazzocco MM <em>Cognition and tyrosine supplementation among school-aged children with phenylketonuria<\/em> 1992, American journal of diseases of children (19. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1415060\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 1415060<\/a><\/li>\n<li>Solon-J\u00fanior LJF <em>The effect of tyrosine supplementation on whole-body endurance performance in physically active population: A systematic review and meta-analysis including GRADE qualification<\/em> 2023, Journal of sports sciences. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38290812\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 38290812<\/a><\/li>\n<li>Jongkees BJ <em>Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands&#8211;A review<\/em> 2015, Journal of psychiatric research. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26424423\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 26424423<\/a><\/li>\n<\/ul>\n\n\n\n<p class=\"odczynnik-status\"><strong>Reagent classification.<\/strong> The material is not intended for human use. It is not a veterinary product either. This is a high-purity laboratory reagent intended for analytical work by HPLC and GC-MS. It is not a drug, supplement or food.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zestawienie parametr\u00f3w materia\u0142u Parameter Value Substance L-tyrosine, proteinogenic amino acid, synthetic material CAS registry number 60-18-4 Summary formula C9H11NO3 Formula weight 181.19 Configuration L, single stereocentre in the side chain Appearance White crystalline powder Declared assay Not less than 99 percent of the main component Net mass 1000 mg per sealed unit Solubility character Sparingly [&hellip;]<\/p>\n","protected":false},"featured_media":971,"template":"","meta":[],"product_cat":[164],"product_tag":[227,163,225,229,226,228],"class_list":["post-545","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-uncategorized-en","product_tag-cas-no-60-18-4-en","product_tag-left-tyrosine","product_tag-l-tyrosine-en","product_tag-the-amino-acid-l-tyrosine","product_tag-tyr-en","product_tag-tyrosyl-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.8.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>L-tyrosine powder - specification and purity routes<\/title>\n<meta name=\"description\" content=\"L-tyrosine, CAS 60-18-4, C9H11NO3, formula weight 181.19: specification table, assay routes, chemical against optical purity, dissolution and storage.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L-tyrosine powder - specification and purity routes\" \/>\n<meta property=\"og:description\" content=\"L-tyrosine, CAS 60-18-4, C9H11NO3, formula weight 181.19: specification table, assay routes, chemical against optical purity, dissolution and storage.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/\" \/>\n<meta property=\"og:site_name\" content=\"NONSENSIA, Laboratorium.\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/L-TYROSINEALLEGRO.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"896\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/\",\"url\":\"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/\",\"name\":\"L-tyrosine powder - specification and purity routes\",\"isPartOf\":{\"@id\":\"https:\/\/mebicar.pl\/#website\"},\"datePublished\":\"2022-10-10T08:24:56+00:00\",\"dateModified\":\"2022-10-10T08:24:56+00:00\",\"description\":\"L-tyrosine, CAS 60-18-4, C9H11NO3, formula weight 181.19: specification table, assay routes, chemical against optical purity, dissolution and storage.\",\"breadcrumb\":{\"@id\":\"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/mebicar.pl\/en\/shop-2\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Sklep\",\"item\":\"https:\/\/mebicar.pl\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"L-Tyrosine Crystalline Powder: Specification Sheet and Purity Assessment Routes\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/mebicar.pl\/#website\",\"url\":\"https:\/\/mebicar.pl\/\",\"name\":\"NONSENSIA, Laboratorium.\",\"description\":\"Modafinil, Phenylpiracetam, Bromantane NOOTROPIKI!\",\"publisher\":{\"@id\":\"https:\/\/mebicar.pl\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/mebicar.pl\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/mebicar.pl\/#organization\",\"name\":\"LAB\",\"url\":\"https:\/\/mebicar.pl\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/mebicar.pl\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Nonsensia_Go.png\",\"contentUrl\":\"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Nonsensia_Go.png\",\"width\":2133,\"height\":2133,\"caption\":\"LAB\"},\"image\":{\"@id\":\"https:\/\/mebicar.pl\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"L-tyrosine powder - specification and purity routes","description":"L-tyrosine, CAS 60-18-4, C9H11NO3, formula weight 181.19: specification table, assay routes, chemical against optical purity, dissolution and storage.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/","og_locale":"en_US","og_type":"article","og_title":"L-tyrosine powder - specification and purity routes","og_description":"L-tyrosine, CAS 60-18-4, C9H11NO3, formula weight 181.19: specification table, assay routes, chemical against optical purity, dissolution and storage.","og_url":"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/","og_site_name":"NONSENSIA, Laboratorium.","og_image":[{"width":1280,"height":896,"url":"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/L-TYROSINEALLEGRO.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/","url":"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/","name":"L-tyrosine powder - specification and purity routes","isPartOf":{"@id":"https:\/\/mebicar.pl\/#website"},"datePublished":"2022-10-10T08:24:56+00:00","dateModified":"2022-10-10T08:24:56+00:00","description":"L-tyrosine, CAS 60-18-4, C9H11NO3, formula weight 181.19: specification table, assay routes, chemical against optical purity, dissolution and storage.","breadcrumb":{"@id":"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mebicar.pl\/en\/sklep\/l-tyrosine-2\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mebicar.pl\/en\/shop-2\/"},{"@type":"ListItem","position":2,"name":"Sklep","item":"https:\/\/mebicar.pl\/"},{"@type":"ListItem","position":3,"name":"L-Tyrosine Crystalline Powder: Specification Sheet and Purity Assessment Routes"}]},{"@type":"WebSite","@id":"https:\/\/mebicar.pl\/#website","url":"https:\/\/mebicar.pl\/","name":"NONSENSIA, Laboratorium.","description":"Modafinil, Phenylpiracetam, Bromantane NOOTROPIKI!","publisher":{"@id":"https:\/\/mebicar.pl\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mebicar.pl\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/mebicar.pl\/#organization","name":"LAB","url":"https:\/\/mebicar.pl\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/mebicar.pl\/#\/schema\/logo\/image\/","url":"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Nonsensia_Go.png","contentUrl":"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Nonsensia_Go.png","width":2133,"height":2133,"caption":"LAB"},"image":{"@id":"https:\/\/mebicar.pl\/#\/schema\/logo\/image\/"}}]}},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/product\/545","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/media\/971"}],"wp:attachment":[{"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/media?parent=545"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/product_cat?post=545"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/product_tag?post=545"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}