{"id":536,"date":"2022-10-21T16:04:15","date_gmt":"2022-10-21T16:04:15","guid":{"rendered":"https:\/\/mebicar.pl\/sklep\/viagra-tadalafil-purity-%e2%89%a5-99-1000mg\/"},"modified":"2026-08-13T18:24:26","modified_gmt":"2022-10-21T16:04:15","slug":"tadalafil-2","status":"publish","type":"product","link":"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/","title":{"rendered":"Tadalafil Reagent Powder: Identity Checks, Assay Notes and Batch File"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">What arrives in the package<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The listing covers a single-component crystalline solid packed as a weighed laboratory unit.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Substance name: tadalafil, supplied as a dry powder for analytical work<\/li>\n<li>CAS registry number 171596-29-5, matched against supplier catalogue records<\/li>\n<li>Molecular formula C22H19N3O4 with a formula weight of 389.4<\/li>\n<li>Declared assay of the main component: not less than 99 percent<\/li>\n<li>Net mass of the unit: 1000 mg, sealed in a labelled inner container<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Confirming identity before anything else<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Identity and purity are two separate questions, and identity is settled first.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Read the registry number from the inner label against the certificate header<\/li>\n<li>Record an infrared spectrum and overlay it on a retained reference trace<\/li>\n<li>Match chromatographic retention with a standard injected in the same sequence<\/li>\n<li>Confirm the nominal mass expected from the summary formula by mass spectrometry<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Routine assay technique<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Reversed-phase liquid chromatography with ultraviolet detection is the workhorse for this molecular class.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dissolve in an organic solvent first, then dilute into the mobile phase<\/li>\n<li>Run a gradient when late-eluting related substances have to be resolved<\/li>\n<li>Take area normalisation as a first approximation and an external standard for the reported figure<\/li>\n<li>Inject system suitability solutions before the sample sequence, never afterwards<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Classes of related substances<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Levels belong on the batch certificate, so only the classes are described here.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Unreacted starting material and isolated synthesis intermediates<\/li>\n<li>Stereochemical and positional by-products formed during ring closure<\/li>\n<li>Residual crystallisation solvents, quantified by headspace gas chromatography<\/li>\n<li>Water content by Karl Fischer titration, reported batch by batch<\/li>\n<li>Inorganic residue reported as sulfated ash<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Bench handling and storage<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Keep the powder dry and work inside a ventilated enclosure.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Store the sealed container cool, dry and shielded from daylight<\/li>\n<li>Let the container reach room temperature before opening so moisture does not condense inside<\/li>\n<li>Weigh on a calibrated analytical balance behind a draught shield<\/li>\n<li>Log every withdrawal in the substance ledger with date, mass and operator<\/li>\n<li>Collect residues and rinsings as organic chemical waste<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Paperwork that stays with the sample<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A laboratory unit without its file is an unidentified solid.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Batch number together with the manufacturing date<\/li>\n<li>Certificate of analysis naming the techniques actually applied<\/li>\n<li>Safety data sheet in the language of the receiving laboratory<\/li>\n<li>A retest date rather than an open-ended shelf life statement<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other catalogue items<\/h2>\n\n\n\n<ul class=\"powiazane-odczynniki wp-block-list\">\n<li><a href=\"\/sklep\/cannabidiol-2\/\">CBD \/ Cannabidiol \/ Cannabidiol, Krishals \u2265 99.85% 1000mg!<\/a><\/li>\n<li><a href=\"\/sklep\/sunifiram-2\/\">Sunifiram, pure chemical \u2265 99%. 1000mg.<\/a><\/li>\n<li><a href=\"\/sklep\/l-dopa\/\">L-DOPA \u2265 99%.\u00a0Czysta substancja chemiczna bez wype\u0142niaczy!<\/a><\/li>\n<li><a href=\"\/sklep\/aniracetam\/\">Aniracetam \u2265 99%. Czysta substancja chemiczna bez wype\u0142niaczy 1000mg.<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Selected literature<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Animal and in vitro studies indexed in PubMed; no human-use guidance is provided here.<\/p>\n\n\n\n<ul class=\"pismiennictwo wp-block-list\">\n<li>Greco EA <em>Tadalafil and Steroid Hormones Interactions in Adipose, Bone and Prostate Tissues: Focus on Translational Perspectives<\/em> 2022, International journal of molecular sciences. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35457011\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 35457011<\/a><\/li>\n<li>Gong B <em>Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis<\/em> 2017, International urology and nephrology. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28741090\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 28741090<\/a><\/li>\n<li>Jehle DVK <em>Benefits of Tadalafil and Sildenafil on Mortality, Cardiovascular Disease, and Dementia<\/em> 2025, The American journal of medicine. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39532245\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 39532245<\/a><\/li>\n<li>Sebastianelli A <em>Tadalafil Alone or in Combination with Tamsulosin for the Management for LUTS\/BPH and ED<\/em> 2020, Current urology reports. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33108544\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 33108544<\/a><\/li>\n<\/ul>\n\n\n\n<blockquote class=\"odczynnik-status\"><p>Material status. It is not a substance for human use. No veterinary applications are provided for. This is a high-purity laboratory reagent intended for analytical work by HPLC and GC-MS. Outside the category of medicinal and food products.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>What arrives in the package The listing covers a single-component crystalline solid packed as a weighed laboratory unit. Substance name: tadalafil, supplied as a dry powder for analytical work CAS registry number 171596-29-5, matched against supplier catalogue records Molecular formula C22H19N3O4 with a formula weight of 389.4 Declared assay of the main component: not less [&hellip;]<\/p>\n","protected":false},"featured_media":517,"template":"","meta":[],"product_cat":[164],"product_tag":[188,187,189],"class_list":["post-536","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-uncategorized-en","product_tag-cas-number-171596-29-5-en","product_tag-tadalafil-en","product_tag-viagra-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.8.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Tadalafil reagent - identity, assay and batch notes<\/title>\n<meta name=\"description\" content=\"Tadalafil as a laboratory powder: CAS 171596-29-5, formula C22H19N3O4, HPLC assay routine, impurity classes and the contents of the batch file.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tadalafil reagent - identity, assay and batch notes\" \/>\n<meta property=\"og:description\" content=\"Tadalafil as a laboratory powder: CAS 171596-29-5, formula C22H19N3O4, HPLC assay routine, impurity classes and the contents of the batch file.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/\" \/>\n<meta property=\"og:site_name\" content=\"NONSENSIA, Laboratorium.\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Tadalafil_Viagra_Sklep_Kup-1024x768.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"768\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/\",\"url\":\"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/\",\"name\":\"Tadalafil reagent - identity, assay and batch notes\",\"isPartOf\":{\"@id\":\"https:\/\/mebicar.pl\/#website\"},\"datePublished\":\"2022-10-21T16:04:15+00:00\",\"dateModified\":\"2022-10-21T16:04:15+00:00\",\"description\":\"Tadalafil as a laboratory powder: CAS 171596-29-5, formula C22H19N3O4, HPLC assay routine, impurity classes and the contents of the batch file.\",\"breadcrumb\":{\"@id\":\"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/mebicar.pl\/en\/shop-2\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Sklep\",\"item\":\"https:\/\/mebicar.pl\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Tadalafil Reagent Powder: Identity Checks, Assay Notes and Batch File\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/mebicar.pl\/#website\",\"url\":\"https:\/\/mebicar.pl\/\",\"name\":\"NONSENSIA, Laboratorium.\",\"description\":\"Modafinil, Phenylpiracetam, Bromantane NOOTROPIKI!\",\"publisher\":{\"@id\":\"https:\/\/mebicar.pl\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/mebicar.pl\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/mebicar.pl\/#organization\",\"name\":\"LAB\",\"url\":\"https:\/\/mebicar.pl\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/mebicar.pl\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Nonsensia_Go.png\",\"contentUrl\":\"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Nonsensia_Go.png\",\"width\":2133,\"height\":2133,\"caption\":\"LAB\"},\"image\":{\"@id\":\"https:\/\/mebicar.pl\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Tadalafil reagent - identity, assay and batch notes","description":"Tadalafil as a laboratory powder: CAS 171596-29-5, formula C22H19N3O4, HPLC assay routine, impurity classes and the contents of the batch file.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/","og_locale":"en_US","og_type":"article","og_title":"Tadalafil reagent - identity, assay and batch notes","og_description":"Tadalafil as a laboratory powder: CAS 171596-29-5, formula C22H19N3O4, HPLC assay routine, impurity classes and the contents of the batch file.","og_url":"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/","og_site_name":"NONSENSIA, Laboratorium.","og_image":[{"width":1024,"height":768,"url":"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Tadalafil_Viagra_Sklep_Kup-1024x768.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/","url":"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/","name":"Tadalafil reagent - identity, assay and batch notes","isPartOf":{"@id":"https:\/\/mebicar.pl\/#website"},"datePublished":"2022-10-21T16:04:15+00:00","dateModified":"2022-10-21T16:04:15+00:00","description":"Tadalafil as a laboratory powder: CAS 171596-29-5, formula C22H19N3O4, HPLC assay routine, impurity classes and the contents of the batch file.","breadcrumb":{"@id":"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mebicar.pl\/en\/sklep\/tadalafil-2\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mebicar.pl\/en\/shop-2\/"},{"@type":"ListItem","position":2,"name":"Sklep","item":"https:\/\/mebicar.pl\/"},{"@type":"ListItem","position":3,"name":"Tadalafil Reagent Powder: Identity Checks, Assay Notes and Batch File"}]},{"@type":"WebSite","@id":"https:\/\/mebicar.pl\/#website","url":"https:\/\/mebicar.pl\/","name":"NONSENSIA, Laboratorium.","description":"Modafinil, Phenylpiracetam, Bromantane NOOTROPIKI!","publisher":{"@id":"https:\/\/mebicar.pl\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mebicar.pl\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/mebicar.pl\/#organization","name":"LAB","url":"https:\/\/mebicar.pl\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/mebicar.pl\/#\/schema\/logo\/image\/","url":"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Nonsensia_Go.png","contentUrl":"https:\/\/mebicar.pl\/wp-content\/uploads\/2022\/10\/Nonsensia_Go.png","width":2133,"height":2133,"caption":"LAB"},"image":{"@id":"https:\/\/mebicar.pl\/#\/schema\/logo\/image\/"}}]}},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/product\/536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/media\/517"}],"wp:attachment":[{"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/media?parent=536"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/product_cat?post=536"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mebicar.pl\/en\/wp-json\/wp\/v2\/product_tag?post=536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}