{"id":532,"date":"2022-10-02T07:40:48","date_gmt":"2022-10-02T07:40:48","guid":{"rendered":"https:\/\/mebicar.pl\/sklep\/l-dopa-%e2%89%a5-99-pure-chemical-substance-without-fillers\/"},"modified":"2026-09-01T01:26:51","modified_gmt":"2026-09-01T01:26:51","slug":"l-dopa-2","status":"publish","type":"product","link":"https:\/\/mebicar.pl\/en\/sklep\/l-dopa-2\/","title":{"rendered":"L-DOPA 1 g \u2014 Intake, Control and Custody Protocol for the Reagent Store"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Levodopa is an amino acid carrying a catechol ring, and that ring governs how the container is handled once it arrives. The sequence below is written as a store protocol rather than as a product description. See also our laboratory reagent: <a href=\"\/sklep\/l-phenylalanine\/\">Fenyloalanina \/ L-Phenylalanine \u2265 99% 1000mg<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Step one: intake of the container<\/h2>\n\n\n\n<ol class=\"wp-block-list\"><li>Compare the label against the order: registry number 59-92-7, formula C9H11NO4, molar mass 197.19, net mass 1 g.<\/li><li>Confirm that the certificate of analysis in the box carries the same batch number as the jar, and reject the delivery if it does not.<\/li><li>Record appearance in the intake note; the material is described as a white crystalline solid, and any yellow or grey cast is written down before the jar is stored.<\/li><li>Enter the batch into the reagent register with the delivery date, the retest date and the shelf location.<\/li><li>File the safety data sheet in its current version alongside the certificate.<\/li><\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">The appearance check is not cosmetic: a catechol is oxidation-prone, and darkening is the visible end of a process that has already changed the material. See also our catalogue listing: <a href=\"\/sklep\/acetyl-l-carnitine\/\">ALCAR \/ Acetyl-L-Carnitine &#8211; Purity \u2265 99% net weig<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Step two: control before release to a method<\/h2>\n\n\n\n<ol class=\"wp-block-list\"><li>Read which method produced the assay figure on the certificate, and whether the figure is chromatographic or titrimetric.<\/li><li>Check that optical purity is addressed, either by specific rotation or by a chiral chromatographic determination, since the D form is a distinct article.<\/li><li>Confirm that water content is reported separately from the assay.<\/li><li>Confirm that residual solvents were tested against the manufacturing route rather than a generic list.<\/li><li>Only then release the batch and note the release in the register with a signature.<\/li><\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">Optical purity deserves the second position on that list. The two enantiomers share a formula, a mass and an ultraviolet spectrum, so a routine assay cannot separate them; only a chiral method or a polarimetric measurement can. A lot released without that line on the certificate is released on an assumption.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Step three: storage and each subsequent opening<\/h2>\n\n\n\n<ol class=\"wp-block-list\"><li>Store cool, dry and dark, in the original tightly closed container.<\/li><li>Equilibrate a cold container to room temperature before opening, so that condensation does not settle on the crystals.<\/li><li>Weigh promptly, reclose immediately and return the jar to its shelf position rather than leaving it on the bench.<\/li><li>Note date, mass taken and the person taking it, one line per withdrawal.<\/li><li>Inspect the remaining material at every opening and stop using the batch if the colour has shifted.<\/li><\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">Water solubility is limited here, so working solutions are prepared fresh, and any solution that develops colour on standing is discarded rather than filtered: the colour is the reaction product itself.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Step four: closing the batch<\/h2>\n\n\n\n<ol class=\"wp-block-list\"><li>Record the final withdrawal and the residual mass.<\/li><li>Dispose of the remainder through the chemical waste route, never through the sink.<\/li><li>Keep the certificate, chromatograms and register entries after the jar is gone, for as long as the results derived from it are in use.<\/li><\/ol>\n\n\n\n<h2 class=\"wp-block-heading\">Other catalogue items<\/h2>\n\n\n\n<ul class=\"powiazane-odczynniki wp-block-list\">\n<li><a href=\"\/sklep\/acetyl-l-carnitine\/\">ALCAR \/ Acetyl-L-Carnitine &#8211; Purity \u2265 99% net weight 1000mg.<\/a><\/li>\n<li><a href=\"\/sklep\/l-phenylalanine\/\">Fenyloalanina \/ L-Phenylalanine \u2265 99% 1000mg<\/a><\/li>\n<li><a href=\"\/sklep\/mebicar-2\/\">Mebicar \/ Mebicar \/ Temgicoluril &#8211; 30x capsules 100mg. Purity \u2265 99%<\/a><\/li>\n<li><a href=\"\/sklep\/cannabidiol-2\/\">CBD \/ Cannabidiol \/ Cannabidiol, Krishals \u2265 99.85% 1000mg!<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">References<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Animal and in vitro studies indexed in PubMed; no human-use guidance is provided here.<\/p>\n\n\n\n<ul class=\"pismiennictwo wp-block-list\">\n<li>Nutt JG <em>Pharmacokinetics and pharmacodynamics of levodopa<\/em> 2008, Movement disorders : official journal of the. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18781675\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 18781675<\/a><\/li>\n<li>Klawans HL <em>Levodopa-induced myoclonus<\/em> 1975, Archives of neurology. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1079721\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 1079721<\/a><\/li>\n<li>Morris JG <em>A review of some aspects of the pharmacology of levodopa<\/em> 1978, Clinical and experimental neurology. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/386308\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 386308<\/a><\/li>\n<li>Goetz CG <em>Influence of COMT inhibition on levodopa pharmacology and therapy<\/em> 1998, Neurology. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9591519\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 9591519<\/a><\/li>\n<\/ul>\n\n\n\n<h2>Reagent classification<\/h2>\n<p>It is not a substance for human use. It is not a veterinary product either. A high-purity laboratory product used in HPLC and GC-MS studies. Not a medicine, medical device or food product.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Levodopa is an amino acid carrying a catechol ring, and that ring governs how the container is handled once it arrives. The sequence below is written as a store protocol rather than as a product description. See also our laboratory reagent: Fenyloalanina \/ L-Phenylalanine \u2265 99% 1000mg. Step one: intake of the container Compare the [&hellip;]<\/p>\n","protected":false},"featured_media":984,"template":"","meta":[],"product_brand":[],"product_cat":[164],"product_tag":[181,180,179],"class_list":["post-532","product","type-product","status-publish","has-post-thumbnail","product_cat-uncategorized-en","product_tag-d-dopa-en","product_tag-dopa-en","product_tag-l-dopa-en","first","outofstock","shipping-taxable","purchasable","product-type-variable"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>L-DOPA 1 g Reagent \u2014 Intake and Custody Protocol<\/title>\n<meta name=\"description\" content=\"Levodopa (L-DOPA), CAS 59-92-7, C9H11NO4, mass 197.19: intake checks, optical purity, catechol oxidation control, storage steps and batch release records.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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