{"id":524,"date":"2022-10-05T06:14:15","date_gmt":"2022-10-05T06:14:15","guid":{"rendered":"https:\/\/mebicar.pl\/sklep\/pramiracetam-purity-of-substance-%e2%89%a5-99-1000mg\/"},"modified":"2026-08-13T18:24:26","modified_gmt":"2022-10-22T17:33:24","slug":"pramiracetam-purity-of-substance-%e2%89%a5-99-1000mg","status":"publish","type":"product","link":"https:\/\/mebicar.pl\/en\/sklep\/pramiracetam-purity-of-substance-%e2%89%a5-99-1000mg\/","title":{"rendered":"Pramiracetam 1 g \u2014 Reagent Notes on Identity, Assay and Storage"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Identity at a glance<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Four fields identify this material in a reagent register; the trade name is not one of them.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>CAS number 68497-62-1, the only unambiguous handle when ordering, filing or disposing of the container.<\/li><li>Molecular formula C14H27N3O2 with a molecular weight of 269.38, taken from supplier and database records.<\/li><li>Structure: a 2-oxopyrrolidin-1-yl acetamide backbone carrying a diisopropylaminoethyl side chain, which makes the molecule an amine base as well as an amide.<\/li><li>Physical form: white to beige powder according to supplier datasheets, supplied here as a 1 g unit.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What an assay figure actually covers<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A stated purity of 99 percent is a chromatographic statement about one method. It is not a global claim about everything inside the jar.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Area-normalised liquid chromatography with ultraviolet detection reports what the detector can see, and says nothing about water, inorganic salts or non-absorbing residues.<\/li><li>A separate water determination by Karl Fischer titration closes that gap and belongs on the certificate.<\/li><li>Residual solvents are a headspace gas chromatography question, run against the solvent list of the actual synthetic route.<\/li><li>Structural confirmation comes from proton and carbon nuclear magnetic resonance spectra compared with a reference batch.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Handling a low-melting solid<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Supplier datasheets place the melting range of this compound near 47 to 48 degrees Celsius, which is low for a weighing-room powder.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep the container away from radiators, lamp housings and sunlit benches, since softening changes flow and complicates weighing.<\/li><li>Let a cold-stored container equilibrate to room temperature before opening, so condensation forms outside the powder rather than in it.<\/li><li>Weigh promptly and reclose; an amine base left open to laboratory air is not chemically neutral over long exposure.<\/li><li>Record tare, net mass and balance identifier on one line of the notebook, not across three.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Solubility as a working parameter<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The compound dissolves in water and in dimethyl sulfoxide, and that decides how stock solutions are built.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Aqueous stocks are convenient and are best prepared fresh wherever the analytical method allows it.<\/li><li>Stocks in dimethyl sulfoxide need the solvent lot noted, because its own water content varies between bottles.<\/li><li>Each stock carries substance, concentration, solvent, date and initials; the first four are worthless without the date.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Batch paperwork worth keeping<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The certificate of analysis is the only document that ties every number above to the specific jar on the shelf.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Batch number and manufacturing date, copied into the reagent register at intake rather than later.<\/li><li>Chromatograms and spectra as delivered, archived together with the certificate and not in a separate folder.<\/li><li>Retest or expiry date, with the storage conditions the supplier assumed when setting it.<\/li><li>Current safety data sheet, filed where bench staff can reach it without asking anyone.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other catalogue items<\/h2>\n\n\n\n<ul class=\"powiazane-odczynniki wp-block-list\">\n<li><a href=\"\/sklep\/mebicar\/\">Mebicar \/ Mebikar \/ Temgicoluril &#8211;  Czysto\u015b\u0107 \u2265 99%<\/a><\/li>\n<li><a href=\"\/sklep\/cdp-choline\/\">CDP cholina \u2265 99%, 1000mg<\/a><\/li>\n<li><a href=\"\/sklep\/acetyl-l-carnitine\/\">ALCAR \/ Acetyl-L-Carnitine &#8211; Purity \u2265 99% net weight 1000mg.<\/a><\/li>\n<li><a href=\"\/sklep\/l-phenylalanine\/\">Fenyloalanina \/ L-Phenylalanine \u2265 99% 1000mg<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">References<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Animal and in vitro studies indexed in PubMed; no human-use guidance is provided here.<\/p>\n\n\n\n<ul class=\"pismiennictwo wp-block-list\">\n<li>Fang Z <em>[Pharmacokinetics of pramiracetam in animals]<\/em> 1999, Hua xi yi ke da xue xue bao = Journal of Wes. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11387954\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 11387954<\/a><\/li>\n<li>Claus JJ <em>Nootropic drugs in Alzheimer&#x27;s disease: symptomatic treatment with pramiracetam<\/em> 1991, Neurology. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2011259\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 2011259<\/a><\/li>\n<li>Murray CL <em>The effect of pramiracetam (CI-879) on the acquisition of a radial arm maze task<\/em> 1986, Psychopharmacology. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3088666\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 3088666<\/a><\/li>\n<li>Maresov\u00e1 D <em>The action of pramiracetam on consequences of hypobaric hypoxia is only moderate<\/em> 1996, Physiological research. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9200217\/\" rel=\"nofollow noopener\" target=\"_blank\">PMID 9200217<\/a><\/li>\n<\/ul>\n\n\n\n<div class=\"odczynnik-status\"><p><strong>Reagent classification.<\/strong> Human use is outside the scope of this product. The material is not a veterinary product. It is a high-purity laboratory product for research using HPLC and GC-MS. Outside the category of medicinal and food products.<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Pramiracetam a molecule in the racetam family designed to reverse neurodegradative processes. The agent has been tested on patients with brain injuries. One of the few molecules that has been tested on patients with physical brain injuries.<\/p>\n","protected":false},"featured_media":953,"template":"","meta":[],"product_brand":[],"product_cat":[164],"product_tag":[165,170,169,167,166,168],"class_list":["post-524","product","type-product","status-publish","has-post-thumbnail","product_cat-uncategorized-en","product_tag-cas-no-68497-62-1-en","product_tag-concussion-en","product_tag-parke-davis-en","product_tag-pramiracetam-en","product_tag-stimulant","product_tag-warner-lambert-en","first","instock","shipping-taxable","purchasable","product-type-variable"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Pramiracetam Reagent 1 g \u2014 Identity and Assay Notes<\/title>\n<meta name=\"description\" content=\"Pramiracetam reagent notes: CAS 68497-62-1, formula C14H27N3O2, mass 269.38, low melting solid, assay by chromatography, water content and batch 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