Modafinil – what is it?

Modafinil, pure chemical 99%

CAS No.: 68693-11-8

Modafinil is an organic compound with psychostimulant effects. Also available as Fl Modafinil. It is used successfully around the world by people needing to support brain function, alertness and mental performance. It’s not addictive, it’s efficient, and it lasts several hours or so.

The effect of the product comes down to the normalization of the diurnal rhythm, that is, the state of wakefulness and sleep. It is counted among the eugeroics, which are compounds that reduce drowsiness and put the body into a state of wakefulness. In addition, the product exhibits nootropic activity, improving such mental functions as memory, concentration and motivation. To purchase modafinil, a prescription is not needed.

Modafinil – application

The primary use of the compound is to counter narcolepsy, or excessive daytime sleepiness. The effectiveness of supplementation has also been confirmed for moderate to severe sleep problems. The benefits of taking the product can be felt by those who work in shift work. When such people use modafinil, the effects are spectacular and include normalization of the diurnal rhythm and improved mood and increased productivity during the night shift.

The product improves cognitive function, thus supporting learning processes. Among users of modafinil, opinions are unanimous – the compound improves memory and concentration, accelerates information processing. It can also be used to reduce chronic fatigue syndrome and the brain fog phenomenon. It is therefore recommended for students or white-collar workers, as is Sunifiram.

Other possible uses for the product include alleviating symptoms of ADHD, obstructive sleep apnea, or supporting addiction therapy.

Mechanism of action of modafinil

Modafinil works through several mechanisms. The most important of these is the inhibition of dopamine and norepinephrine reuptake. This has the effect of increasing motivation, creativity and endurance. The compound decreases extracellular GABA levels, enhancing the effects of glutamate. This translates into the occurrence of a stimulating effect, as well as improved neuroplasticity of the brain. In addition, the compound promotes the release of histamine and serotonin.

Modafinil dosage

The recommended dosage is 100-200 mg per day, and in less sensitive people the dose can be increased to 300 mg. The compound persists in the blood for up to 12 hours. Therefore, it is not frequent to reach for another tablet.


  1. Hart CL, Haney M, Vosburg SK, Comer SD, Gunderson E, Foltin RW. Modafinil attenuates disruptions in cognitive performance during simulated night-shift work. Neuropsychopharmacology. 2006 Jul;31(7):1526-36;
  2. U. Müller et al. ,Effects of modafinil on non-verbal cognition, task enjoyment and creative thinking in healthy volunteers, Neuropharmacology. 2013 Jan; 64(5): 490-495;
  3. H Moldofsky et al. “A randomized trial of the long-term, continued efficacy and safety of modafinil in narcolepsy” Sleep Medicine, Volume 1, Issue 2, April 1, 2000, Pages 109-116;
  4. Maarten E.A. Reith et al. “Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter” Drug Alcohol Depend. 2015 Feb 1; 0: 1-19.

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